Before using commercial brand cleaners try:
Vinegar and Water
Never use Window cleaner, Acetone or Ammonia based products on acrylic.
Never use rubber mats or no slip adhesive strips on acrylic surfaces, bacterial mold will penetrate the finish under them.
Waxing the finish with an automotive type car wax is recommended to keep surface spot free, however do not wax the base area it will be slippery.